The Professor Layton games are such a huge blindspot for me. I think I would like them but I just never got around to playing them. The only one I have is the crossover with Phoenix Wright and I haven't played that either.
I don't know if your aging reflexes will cause you any trouble with Ninja Gaiden: Dragon Sword, but I did not think the stylus controls were a hindrance to the gameplay at all. It was a great play experience. Of course, I was a teenager when I played it, so take that all with a grain of salt lol



